Rise of Christianity in Medieval Europe

Christianity started humbly as a Jewish sect in Roman-dominated Palestine, but it grew to become a continental and world religion in the middle ages. Certain qualities in Christianity were responsible for this radical outcome. First, Jesus’ message represented a radical departure from traditional religions at the time.Advertising We will write a custom essay sample on Rise of Christianity in Medieval Europe specifically for you for only $16.05 $11/page Learn More Furthermore, the early Church remained zealous about their calling to spread the message. Several social and cultural features attracted the Gentiles to the faith. However, this growth changed dramatically in the middle ages when the Roman Catholic Church took up political responsibilities. Jesus’ message was a ‘revolution’ during those ancient times. He claimed that he was the messiah. He added that he was the only way that Yahweh would restore the Israelites to their former glory (McManners 9). The Israelites had gone through numerous trails and tribulations. Jesus claimed that he would save them from these afflictions. They would realize their complete liberation through him. This was something that other notable Israelites had never claimed before. Furthermore, Jesus stated that he was the son of God and that he had come to die for other people’s sins. In the past, Israelites made atonement for their sin through animal sacrifices. However, when Jesus came, he claimed that he would save them from their sins through his death. He articulated this during the Passover feast in the temple. At the time, Jesus said that, through his death, he would do for Israel what they could not do for themselves. Jesus’ message was something akin to a revolution because it represented the presence of God among the Israelites. Before this, God had sent other messengers to deliver information to the Jews, but this time, it was God himself who was liv ing among the people. The Israelites believed that God manifested himself through the use of the Torah, divine wisdom, and the temple, but with Jesus’ entry, a different manifestation took effect. His work was also symptomatic of this very message. Jesus’ message was not the only thing that caused a lot of controversy among the Jewish population. The Jews and the Romans had numerous political, social and religious reasons why they opposed this man. They thought of him as a threat to the Roman Empire. During Jesus’ death, Pilate was Judea’s ruler; he felt responsible for the maintenance of peace in this area.Advertising Looking for essay on history? Let's see if we can help you! Get your first paper with 15% OFF Learn More Since the Jewish authorities wanted him dead, he felt obligated to obey their wishes in order to maintain peace. The Jewish leaders wanted to kill Jesus because he seemed to have contradicted the Ten Commandments. The first law states that the Israelites were to have no other gods other than Yahweh. The Sanhedrin had not listened to Jesus’ message well, so they assumed that he was blaspheming. The Israelites called Jesus the King of the Jews during his last years. This made the Sanhedrin jealous because he seemed more popular than they were. Furthermore, Jesus told the Jewish people that he would destroy the temple and build a new one. When the Jewish priests heard about this, they felt threatened because they realized that their authority would not be necessary. In order to preserve their position, they needed to eliminate this person who would invalidate them. Therefore, the Jewish leaders requested the Roman authorities to kill Jesus. After Christ’s death, the controversies did not end there; almost all quarters persecuted the early Christians. In certain instances, it was the Jews; in other scenarios, it was the Romans. The latter group had developed a distaste for Christianity owing to political and social reasons. In Romanic eyes, religion was not a separate entity from politics. They saw it as a way of preserving the sense of well being and order in the Roman Empire. Therefore, if another part of the empire tried to separate itself from the rest of the group, then this would spark hostility from the natives. They regarded Christianity as a serious threat to the unity of the Roman Empire. The Romans regarded Christians as antisocial because they had their own customs and practices. For instance, they spoke of the love feasts as well ‘drinking Jesus’ Blood’ and eating his body. These seemed like odd behaviors to the Romans who believed that the Jews were cannibals and immoral people. In fact, in the 2nd Century, the Romans accused Lyons martyrs of Oedipian intercourse and other orgies (Frend 7). One lawyer even stated that they had engaged in incestuous acts. Ignorance led to these misconceptions, but the Christian’s mysteriousness a lso contributed. The Roman Empire experienced some problems in the fifth Century. At this time, its people believed that they were in trouble because the gods were angry at them. They blamed Christians for making these continuous changes in their lives. The Romans called the Christians atheists because they had rejected the deities of the Roman Empire. The Romans always believed that delineation from the gods was a source of bad luck, and this took effect for many years to come. Despite the persecutions and horrific punishments, the Christian faith still spread so quickly. This occurred because Christianity was open to non Jews. In the beginning, the Christians tried to change the Jews, but it was only they after opening up to the rest of the world that they started expanding so quickly.Advertising We will write a custom essay sample on Rise of Christianity in Medieval Europe specifically for you for only $16.05 $11/page Learn More The Gentiles accounte d for the highest number of converts at the time. Nonetheless, these groups liked certain qualities found in Christianity. First, Christians disregarded the need to follow strict dietary laws or even practice male circumcision. Consequently, the Gentiles felt that they would fit into the group rather well. The most significant feature of Christianity that caused the Gentiles to consider it was its powerful message. Christians affirmed that they had come to bring salvation to the full human race. They did not care whether one was a servant or a master; all one needed was to believe in this God. At that time, society had various classes; consequently, the oppressed members felt that they would belong in this new faith. Christianity also grew quickly because it was not substantially different from pagan religions of the time. For example, the Egyptian goddess called Isis was quite similar to Mary because Mary was the mother of Jesus, who was also God. Christians chose to celebrate Jesu s’ birth on the 25th day of December rather than 6th January because the Christians at that time related to a pagan holiday. Many of them would join in the pagan celebrations even though they did not profess to their beliefs. Additionally, the Christians recognized the use of the rabbit and the egg during Easter. They borrowed this from another pagan practice. Contrary to Romanic expectations, the persecutions of Christians also contributed to the spread of Christianity. Instead of shunning this religion, many followers felt that it was quite honorable to die for what one believed in. Consequently, they embraced this possibility of death by claiming that it was a way of proving their worth before God. The church’s structure had a role to play in the development of the church. This organized structure contributed to further expansion of the religion. Lastly, Christianity grew quickly because of the missionaries involved in spreading the Gospel. In those early centuries, there was relative peace and stability. This aided the missionaries in their work because they could travel by sea to different corners of the world (McManners 44). The Church continued to grow, and started to become massive in the middle ages. However, because the church had taken on a political dimension, it started departing from the original teaching of the messiah. From as early as five hundred and ninety BC, the Roman Catholic Church declared the Pope as the servant of servants. Submission to the Pope was imperative for salvation. When one opposed the ruling of the Roman Catholic Church, then that person would be excommunicated. Furthermore, they claimed that one would lose one’s soul. The Church started loosing its belief in salvation by faith in Jesus.Advertising Looking for essay on history? Let's see if we can help you! Get your first paper with 15% OFF Learn More From 14C AD, the Roman Catholic Church disregarded Augustinian teachings and embraced the Pelagius teaching. One would gain salvation through submission to the church and external obedience. The concept of living a faith-based life was not significant. Issues of sainthood came up; they claimed that one could reach sinless perfection through continual reception of grace. If one had not reached this level of perfection upon death, then one would go to purgatory. Some individuals even started to worship the saints as they acted as mediators between man and God. However, this differed from Christ’s teaching because Christ talked about justification; He died in order to justify believers by faith rather than sanctify them. The clergy became extremely powerful at the time. In addition, the Church introduced indulgences where priests would offer their services for sale. For instance, when one committed incest, one would pay five goats. They even had prices for murder, burglary, and deceit. All these activities contradicted the message of free salvation and forgiveness of sin as taught by Christ. The Roman Church controlled philosophies, morals, education, politics and religion itself. The middle ages were a dark time for Christianity because the faithful forgot fundamental Christian doctrines. The Christian faith is one of the most resilient churches in the world. It started with Jesus’ rejection and death; thereafter, the Romans persecuted the early Christians. However, its unique message drew the Gentiles to the church and accounted for its quick spread. The middle ages epitomized the distortion of the Christian message through excessive corruption of Christian doctrines by the Roman Catholic Church. Works Cited Frend, WIlliam. â€Å"Persecution in the Early Church.† Christian history, 27.3(2000): 7 McManners, John. The Oxford Illustrated History of Christianity. Madrid: OUP, 1999. Print. This essay on Rise of Christianity in Medieval Europe was written and submitted by user Chaim Schmidt to help you with your own studies. You are free to use it for research and reference purposes in order to write your own paper; however, you must cite it accordingly. You can donate your paper here.

History of Photography and the Camera (Timeline)

History of Photography and the Camera (Timeline) Several important achievements and milestones dating back to the ancient Greeks have contributed to the development of cameras and photography.   Here is a brief time timeline of the various breakthroughs with a description of its importance.   5th-4th Centuries B.C. Chinese and Greek philosophers describe the basic principles of optics and the camera. 1664-1666 Isaac Newton discovers that white light is composed of different colors. 1727 Johann Heinrich Schulze discovered that silver nitrate darkened upon exposure to light. 1794 First Panorama opens, the forerunner of the movie house invented by Robert Barker. 1814 Joseph Niepce achieves first photographic image using  an early device for projecting real-life imagery called a  camera obscura. However, the image required eight hours of light exposure and later faded. 1837 Louis Daguerres first daguerreotype, an image that was fixed and did not fade and needed under thirty minutes of light exposure. 1840 First American patent issued in photography to Alexander Wolcott for his camera. 1841 William Henry Talbot patents the Calotype process,  the first negative-positive process making possible the first multiple copies. 1843 The first advertisement with a photograph is published in Philadelphia. 1851 Frederick Scott Archer invented the Collodion process  so that images required only two or three seconds of light exposure. 1859 Panoramic camera, called  the Sutton, is  patented. 1861 Oliver Wendell Holmes invents stereoscope viewer. 1865 Photographs and photographic negatives are added to protected works under copyright law. 1871 Richard Leach Maddox invented the gelatin dry plate silver bromide process, which means negatives no longer had to be developed immediately. 1880 Eastman Dry Plate Company is founded. 1884 George Eastman invents flexible, paper-based photographic film. 1888 Eastman patents Kodak roll-film camera. 1898 Reverend Hannibal Goodwin patents celluloid photographic film. 1900 First mass-marketed camera, called the Brownie, goes on sale. 1913/1914 First 35mm still camera is developed. 1927 General Electric invents the modern flash bulb. 1932 First light meter with photoelectric cell is  introduced. 1935 Eastman Kodak markets Kodachrome film. 1941 Eastman Kodak introduces Kodacolor negative film. 1942 Chester Carlson receives a patent for electric photography (xerography). 1948 Edwin Land launches and  markets the Polaroid camera. 1954 Eastman Kodak introduces high-speed Tri-X film. 1960 EGG develops extreme depth underwater camera for U.S. Navy. 1963 Polaroid introduces the instant color film. 1968 Photograph of the Earth is taken from the moon. The photograph, Earthrise, is considered one of  the most influential environmental photographs ever taken. 1973 Polaroid introduces one-step instant photography with the SX-70 camera. 1977 Pioneers  George Eastman and Edwin Land are  inducted into the National Inventors Hall of Fame. 1978 Konica introduces the first point-and-shoot autofocus camera. 1980 Sony demonstrates first consumer camcorder for capturing moving picture. 1984 Canon demonstrates first digital electronic still camera. 1985 Pixar introduces the digital imaging processor. 1990 Eastman Kodak announces Photo Compact Disc as a digital image storage medium. 1999 Kyocera Corporation introduces the VP-210 VisualPhone, the worlds first mobile phone with built-in camera for recording videos and still photos.

Lysistrata play Essay Example | Topics and Well Written Essays - 500 words

Lysistrata play - Essay Example Macleod made me love the play Lysistrata even more. This is a reaction paper to the play Lysistrata by â€Å"Naked Feet productions†. Hannah Tsapatoris MacLeod proved that she was not an amateur, but a respected director of Greek plays. As a founder and director at â€Å"Naked Feet productions†, she showed her prowess by bringing a team together with the aim of performing the play Lysistrata. Her experiences include performing, choreographing, writing, singing, directing and teaching art. The following are the characters in the play. Kalonike was played by Meryl Lynn Brown, Myrrhine played by Jill Lawrence, Lampito played by Eleonore Thomas, Isemenia played by Cathrene Mary Moroney, Kinesius played by William Crawford, Senator played by Daniel Tobin, Panny played by Lawrence Beck and lastly, Aristophanes played by Robert Zaller. The production featured hotchpotch of ages, costume, attire and acting styles that transformed the acting into a splendid experience. The director through the play exceptionally brought the themes of war and women’s role in society to light. Lili Beta, a renowned Greek performer who played as Lysistrata quantified this through investing enthusiasm and effort in her character. Rallying women to go against their men particularly in a chauvinistic society is quite a difficult task. The production incorporated adapting the play to suite modern times, and in my opinion, MacLeod did a good job on this. The first instance that demonstrated professionalism in the play Lysistrata directed by Macleod was Lysistrata’s accent. This was a clear depiction of Greek accent by Beta, and it intimately linked the play with the audience. In fact, the audiences were seen smiling when the scene called for Lysistrata’s conversation. The words that the audience could use to describe the play are experiences, which were both shocking and amusing. A clear demonstration of

Establish the topic from the paper Essay Example | Topics and Well Written Essays - 500 words

Establish the topic from the paper - Essay Example This reflects cowardice on the behalf of the chosen figures since no one has the courage to take responsibility for their actions. The author places a fraction of the blame on the media since they have the power to change the views and even desires of the masses. They go to the extent of digging up black patches from the history of the individuals who fall on their agenda of getting defamed, while the figures who are favored by them (for some reason) are linked with the hopes and happiness of the nation. The representatives of the parliament are equipped with the power to give their opinions on every matter that is raised in the respective decision making body. The author rightly raises the issue that the intellect and expertise of these individuals is naturally limited to a few fields of life. They might not be familiar with the technicalities of many fields of life but they are granted the right to make a decision about it. This threatens the stability and progress of the bodies fo r which the decision is being taken for. Matters are discussed as if they are a part of a game or race, whereas they should be dealt with productive discussions about the details and repercussions of the solution.

Heart of Darkness by Joseph Conrad. Marlows lie Essay

Heart of Darkness by Joseph Conrad. Marlows lie - Essay Example Marlow’s lie is in the focus of further discussion on the example of his interpretations of Kurtz’s phenomenon. He claims that he does not lie, though he confirms that there were three cases when he lied: the station manager, Kurtz and the Intended heard wrong things from Marlow (Stape, 2004). Marlow lies throughout the novel though contextual background of the novel differs greatly. He is thrown back and forth from savage customs identification and civilized behavior distinction. His further ideas and behavior are developed under conditions of blurred borders between noise of savage and civilization: â€Å"Yet despite Marlow’s insistence, all binary oppositions collapse in the course of his narrative: colonists prove to be conquerors, the gang of virtue is indistinguishable from the gang of greed, the illusions of women merely echo the illusions of men, and there is no clear distinction between lies and truth† (Kaplan 1997, p. 323). This way, Marlowâ€⠄¢s attitude to lie can be interpreted in these frames. Moreover, his acts of lying can be considered on three main backgrounds: his desire to preserve his own ideas about Kurtz, lie as an act of humanity and lie as a means of reality hindrance. Marlow’s lie: lie for what? Generally speaking, Marlow is a complicated and interesting character depicted in the novel. The author intentionally contrasts a human nature to black background. Maybe, Conrad’s intention was to show the darkness of human inner world and not the darkness of African continent: â€Å"The monstrous prevails and the human and artistic potential miscarries. There is a downward tug in Kurtz's involvement with the wilderness and he descends into a brute existence† (Billy 1997, p. 26). Madness dominates in the inner world of Kurtz. Kurtz reflects a dualistic human nature. Lights and darkness exist one by one. When darkness starts prevailing, then anarchy exists everywhere. A strange and dualistic na ture of human darkness can be defined as â€Å"something strange that derives its existence from the hinterland of man's mind, as if it had emerged from the abyss of prehuman ages, or from a superhuman world of contrasting light and darkness. It is a primordial experience which surpasses man's understanding and to which in his weakness he may easily succumb" (Boyle 1964, p. 160). Marlow should not be considered as a liar. He talked about darkness of London in Roman epoch. Romans conquered Britons and Conrad talked about the Belgians conquering Africans. Generally, Conrad intended to show an inner struggle of the self within his inner world. A personified symbolism (Bloom 1987, p. 34) of the ways human soul fights against duality and lie is shown by Conrad throughout the paper. Marlow’s lie is interpreted by Brown (2004) as follows: "Despite his [Marlow's] earlier avowal of a profound aversion to lying, Marlow has already admitted to sacrificing truth to expediency on three p revious occasions" (Brown 2000, p. 14). Still, Brown’s arguments are often criticized. It is necessary to discuss what is lying for Marlow in more details. A breakdown of Marlow's character could be seen when he lied to the Intended. Marlow wanted to give a wrong impression about what happened. Marlow’s intention to give a different representation of real facts to public about himself was seen from the very beginning of the novel, when he sat like Buddha. In that case he wanted to show that he takes nothing with him, but peace. Further wanderings and adventures of Marlow revealed real intentions of this character. Therefore, lying accompanies Marlow throughout the novel. In case when he needed more rivets for his boat, he asked the brickmaker about them but did it through lying.

Use of Protease Inhibitors as Insecticides

Use of Protease Inhibitors as Insecticides The Plagues of Egypt are a well-known to many, to send a message to the Pharaoh, the eighth of which saw Moses have God send was a plague of locusts to destroy crops. Luckily those were mere allegorical stories. What is true is that crop yields for ancient societies have always been plagued pests destroying crops. Even in modern times pests are a major issue for farmers. Effective modern delivery methods of insecticides to fight pests such as chemical sprays like the infamous roundup by Monsanto have proven to be effective, but face issues such as potential poisons lingering in the environment, insects acquiring resistance to them over time, not being very specific in their targets often killing everything they are sprayed on, and tend to be quite toxic. A more effective method has been the use of biological pesticides, where plants in question generate toxins required to fight insects specifically without being toxic. One methods of delivery that has shown promise has been to use pr oteinase inhibitors. Proteases are found in almost all organisms playing important roles in biological processes by breaking down proteins via hydrolytic reactions (Lin et al., 2017). If proteases are overexpressed in a cell it can lead to many proteins being degraded needlessly affecting cell function (Lin et al., 2017). As a result, proteases need to be properly controlled and one of the most efficient ways to do so is with protease inhibitors. When proteinase inhibitors (PIs) bind to digestive enzymes it causes them to become unreactive (Broadway and Duffey, 1986). The pancreas would then have to secrete additional proteinases itself to fight the inhibition from inhibitors so that normal digestion can occur and prevent re-absorption of protease-inhibitor enzyme complex (Broadway and Duffey, 1986). If this process is left unhindered it would lead to loss of essential amino acids which could have be used to build more proteases (Broadway and Duffey, 1986). This loss of amino acids results in an amino ac id deficiency that leads to growth, development and survival issues of the organism (Fatemeh and Bandani, 2011). What makes proteinase inhibitors attractive for controlling pests is that they are encoded by single genes and are effective over wide ranges of pests, making them more practical than methods that rely on inhibiting complex pathways with similar targets (Fatemeh and Bandani, 2011). A substantial amount of development has gone towards finding suitable proteinase inhibitors for plants to express. Insects have also been found to be adapting against the use of protease inhibitors, with some being able to overexpress gut proteases or create new enzymes that are harder to inhibit (Nath et al., 2015). This only shows that the study of proteinase inhibitors still has a long ways to go and will require much more study. Some of the techniques studied in recent years to deter pests include use of trypsin inhibitor against lepidopteran larvae and serine proteinase inhibitors against mosquitos. It was believed that a trypsin inhibitor that was expressed in the germinating seed of Dolichos biflorus would be effective the gut proteins of P. brassicae and S. littoralis. To test this theory researchers extracted the PI from germinating various seed samples then sterilizing seeds in ethanol and water and growing them, collecting the plant seeds from flowering plants at different time intervals and then grinded them up into fine powder and processed it with acetone to get a crude extract (Nath et al., 2015). Researchers were able to measure and extract the amount of trypsin inhibitor in each seed from the crude extract via centrifugation and found that the more days after germination when they extracted the trypsin inhibitor the less the seed had (Nath et al., 2015). This decline coincided with noted decreases in soluble protein activity in the seeds after germination which could be attributed to degradation of proteins including inhibitors and proteases during germination (Nath et al., 2015). To measure trypsin inhibitor effectiveness against gut proteases of organisms, researchers also dissected the midgut of P. brassicae and S. littoralis and centrifuged it to isolate for a source of trypsin, which they found (Nath et al., 2015). To measure activity of inhibitor against gut proteases, researchers measured optical density after mixing inhibitor and gut proteases together (Nath et al., 2015). It was found in this study that all trypsin inhibitors extracted from seeds exhibited inhibitory response against P. brassicae, researchers then took the sample (HPK4) that showed highest inhibitory action and tested it against proteases of S. littoralis, and found that it also exhibited inhibitory activity making it ideal an ideal candidate for an insecticide (Nath et al., 2015). To test inhibitor ability as an insecticide researchers used cabbage leaf discs coated in trypsin inhibitor extracted from HPK4 seeds as it had the highest activity, and fed it to newly hat ched larvae for 5 days (Nath et al., 2015). The experiment measured the amount of the leaf disc eaten and fecal matter produced from larvae over the 5 day period using different concentrations of trypsin inhibitor ranging from 0.025mg to 2.5mg (Nath et al., 2015).ÂÂ   It was found that P. brassicae larvae were sensitive to inhibitor as they showed mortality rate ranging from 10% to 80% (at 0.025mg and 2.5mg concentration respectively) after 5 days of feeding (Nath et al., 2015). Larval fecal matter was also noted to having 38% less gut trypsin and other soluble proteins compared to fecal matter in control samples, and with less of cabbage leaf being eaten in all samples compared to control due to massive dying off of larvae (Nath et al., 2015).ÂÂ   Larval death could be attributed to lack of essential amino acids in insects body due to trypsin inhibitor (Nath et al., 2015). Reduced soluble protein in fecal matter was attributed to less intestinal aberration and the fact th at much less of the leaf was eaten overall (Nath et al., 2015).ÂÂ   Similar results were found in complementary study regarding the effects on S. littoralis, with low survival rates, reduced larval mass, and decreased soluble protein concentration in fecal matter compared to control (Nath et al., 2015). Overall researchers were able to conclude that the PIs (trypsin inhibitor in this case) from various germinating seed strains were able to inhibit gut proteinases of many lepidopteran larvae such as P. brassicae and S. littoralis (Nath et al., 2015).ÂÂ   It is worth noting that while this experiment used PIs as a spray over plants, researchers indicate that this holds promising future for crops to express higher levels of proteinase inhibitors naturally to fight pest populations in a way without spraying toxic pesticides (Nath et al., 2015). Another tested method to fight pests was with serine proteinase inhibitors. Mosquitoes are a major vector of disease carrying with them malaria, west nile virus, and etc, mosquitoes are found around the world and it has been reaffirmed many times that the best way to control mosquitos is through controlling populations (Soares, Soares Torquato, Alves Lemos, Tanaka, 2013).ÂÂ   This topic has been studied extensively and is known that the majority of digestive enzymes for mosquitoes are serine proteases (Soares, Soares Torquato, Alves Lemos, Tanaka, 2013). For this experiment researchers looked into Ae. aegypti a mosquito strain which is found commonly around the world (Soares, Soares Torquato, Alves Lemos, Tanaka, 2013). It was determined that mosquito larvae would be the ideal target for this protease inhibitors because they are aquatic and feed constantly which would give inhibitors the greatest chance to succeed in killing them as they are in early development (Soares, Soar es Torquato, Alves Lemos, Tanaka, 2013). To determine which serine proteases were present in mosquito larvae researchers performed a kinetic assay of larval midgut proteins and determined that the gut extract was a host to trypsin-like, elastase-like, and chymotrypsin-like enzymatic activities (Soares, Soares Torquato, Alves Lemos, Tanaka, 2013). Researchers then used a phage display system to select an inhibitor for all of these digestive proteases, finding that HiTI a trypsin inhibitor from the horn fly would suffice because of successful detection for HiTI on an active M13 phage as it was fused to coat one of the coat proteins (Soares, Soares Torquato, Alves Lemos, Tanaka, 2013).ÂÂ   Researchers then created aÂÂ   combinatorial HiTI inhibitor library and tested for their ability to inhibit the serine proteases in mosquito larvae and their ability to inhibit the trypsin-like, chymotrypsin-like and elastase-like proteases (Soares, Soares Torquato, Alves Lemos, Tanaka, 2013). Amino acid analysis of phagemid DNA indicated that for HiTI, the largest area for variation occurred in the P1 position of the enzyme (Soares, Soares Torquato, Alves Lemos, Tanaka, 2013). This was important because it appeared this position determined the specificity of the HiTI inhibitor, as it was found that if a basic amino acid was present in P1 it would inhibit trypsin, while chymotrypsin would be inhibited if hydrophobic amino acids was present, and if small aliphatic amino acids are present then elastase would be inhibited (Soares, Soares Torquato, Alves Lemos, Tanaka, 2013). Among the library created mutants that would inhibit one of the three noted above were found with majority of clones not being proteases (Soares, Soares Torquato, Alves Lemos, Tanaka, 2013). Researchers then proceeded to purify and clone the HiTI variants into a plamids which experessed in P.pastoris (Soares, Soares Torquato, Alves Lemos, Tanaka, 2013).It was found that the wild type HiTI was able to inhibit the trypsin-like enzymes but not the remaining two (Soares, Soares Torquato, Alves Lemos, Tanaka, 2013). Researchers were able to find 3 mutants that inhibited trypsin-like enzymes but did not inhibit elastase-like and chymotrypsin-like enzymatic reactions, two variants were found to inhibit chymotrypsin with high selectivity for bovine chymotrypsin, one of which (T23) was also found to be an inhibitor for elastase-like proteases as well reaffirming the researchers belief in specific selection by inhibitors for different proteases (Soares, Soares Torquato, Alves Lemos, Tanaka, 2013). The results of this research are promising because this study provides a better understanding of mosquito gut enzymes and provides a framework for insecticide development based on protease inhibitors for mosquitos. In conclusion, it was found that proteinase inhibitors are a viable methods for controlling pests whether it is controlling mosquito populations by feeding larvae serine proteinase inhibitor or coating crops with trypsin inhibitors and feeding it to pests. Much of the work currently has been formed around determining which proteinase inhibitors would match well with their intended target. In order to expand the scope and make proteinases a functional insecticide it would seem more work needs to be done around delivery systems, whether it be as a chemical insecticide spray or genetically altering plants to overexpress proteinase inhibitors. Over time as this field becomes more developed we can be able to determine the effects of these inhibitors on humans. The concept has been proven and more work is needed to make them viable, proteinase inhibitors have a strong future and once the kinks have been worked out then there is no doubt they will be massively successful in increasing crop yields and fighting off pests. References Dantzger, M., Vasconcelos, I. M., Scorsato, V., Aparicio, R., Marangoni, S., Macedo, M. L. R. (2013). Bowman-Birk proteinase inhibitor from Clitoria fairchildiana seeds: Isolation, biochemical properties and insecticidal potential. Phytochemistry, 118(August), 224-235. http://doi.org/10.1016/j.phytochem.2015.08.013 Lin, H., Lin, X., Zhu, J., Yu, X.-Q., Xia, X., Yao, F., You, M. (2017). Characterization and expression profiling of serine protease inhibitors in the diamondback moth, Plutella xylostella (Lepidoptera: Plutellidae). BMC Genomics, 18(1), 162. http://doi.org/10.1186/s12864-017-3583-z Nath, A. K., Kumari, R., Sharma, S., Sharma, H. (2015). Biological activity of Dolichos biflorus L. trypsin inhibitor against lepidopteran insect pests. Indian Journal of Experimental Biology, 53(September), 594-599. Soares, T. S., Soares Torquato, R. J., Alves Lemos, F. J., Tanaka, A. S. (2013). Selective inhibitors of digestive enzymes from Aedes aegypti larvae identified by phage display. Insect Biochemistry and Molecular Biology, 43(1), 9-16. http://doi.org/10.1016/j.ibmb.2012.10.007 Broadway, R. M., Duffey, S. S. (1986). Plant proteinase inhibitors: Mechanism of action and effect on the growth and digestive physiology of larval Heliothis zea and Spodoptera exigua. Journal of Insect Physiology, 32(10), 827-833. http://doi.org/10.1016/0022-1910(86)90097-1 Saadati, F., Bandani, A. R. (2011). Effects of Serine Protease Inhibitors on Growth and Development and Digestive Serine Proteinases of the Sunn Pest, Eurygaster integriceps. Journal of Insect Science (Online), 11(72), 72. http://doi.org/10.1673/031.011.7201

Summary of Boyles Friendly Skies :: essays research papers

T. Coraghessan Boyle’s â€Å"Friendly Skies† is the story of Ellen, a woman who is trying to get to get to New York to be with her mom, but has trouble doing so due to several delays. First, the plane has mechanical problems, this is followed by a pilot claim that they have lost their slots for takeoff. When the plane finally leaves LAX, the engine catches on fire, so emergency landing is required. When back at the airport she is only able to get a non-direct flight that stops in Chicago. While on this flight, Ellen reminisces about heartbreaking details of her past, so she takes prescription medicine with alcohol to try and diminish her pain. Eventually, a nervous man who had annoyed Ellen for hours, threatens to kill everyone because he is not happy with the airline service. With her built up frustration, Ellen picks up a fork and stabs the man repeatedly, which helps in restraining him long enough to land in Denver. The central idea of the story is that even a calm a nd constrained person can have an irrational outburst of emotion if his/her feelings are repressed. The protagonist of the story is Ellen. Ellen is thirty-two years old, with limp blond hair and a plain face and whose eyes oozed sympathy. She is also a fifth-grade teacher who has recently left her job after having experienced the embarrassment of a public fight with her partner Roy in front of her colleagues. From the beginning of the story she is frightened, anxious, with head down and shoulders slumped, indicating she has a lot of pain and suffering kept inside her. Doctors have described her as anemic and depressive and she knows that that life she has led so far has contributed for that diagnosis. The protagonist is a dynamic character because although she starts as a person who keeps all her emotions to herself, in the end, she explodes and releases her frustration on Mr. Lercher, the passenger who tried to kill everyone on the airplane. Her change in attitude can be observed when the narrator describes, â€Å" All she knew was that she’d had enough, enough of Roy and this big, drunken testosterone-addled bully and the miserable, crimpled life that awaited her at her mother’s, and she came up out of her seat as if she’d been launched†¦Ã¢â‚¬  The main conflict is Ellen’s inner conflict and the effect that her repressed feelings have on her life and her attitudes.